HEAP

Human exposome assessment platform

The HEAP project will provide an informatics platform for handling and analysing large amounts of data on environmental exposures and their health effects. The platform will be populated with data from large-population-based cohorts, analysed with high-throughput technologies such as analysis of microbes with metagenomics and analysis of the effects of the environment on the genome (epigenomics). The HEAP platform will also analyse data from large and population-based cohorts on the health effects of purchased products using consumer receipts, and data from volunteer cohorts that carry sensors for continuous monitoring of environmental exposures.

Participants
  • Karolinska Institutet, Sweden (Project Coordination)
  • CSC – IT Center for Science, Finland
  • European Science Infrastructure Services, Finland
  • Logical Clocks AB, Sweden
  • Medical University of Graz, Austria
  • MLC Foundation, Netherlands
  • Statens Serum Institut, Denmark
  • International Agency for Research on Cancer (IARC), France
  • University of Innsbruck, Austria
  • University of Oulu, Finland
  • University of Warsaw, Poland
Coordinator
Prof Joakim Dillner
Scientific Director. Karolinska University Laboratory, Karolinska University Hospital. Head of Unit, Center for Cervical Cancer Prevention
PROJECT MANAGERS

Roxana Merino Martinez

roxana.martinez@ki.se

Helena Andersson

helena.andersson.1@ki.se

Public deliverables

Title Description Ref Participant Format Due
Project Website The HEAP website with information on exposome research in general and the project in particular, with sections targeted either at the scientific community or to the general public. D1.1 IARC website Mar 2020
List of Working Groups and ToR for the WGs – EXPANSE/HEAP A first set of working groups will be made and Term of Reference for the WGs will be specified including the selection of work group leaders, co-leads and members. 12.3 Karolinska Institutet Report Mar 2020
Data Management Plan Data Management Plan – This deliverable will provide the governance and HEAP policies regarding the access, management and sharing of all the used and produced data during and after the project is completed. The plan will cover the generation of metadata from the different data sources of the project including all the cohorts, the raw and processed data and the results to be stored, preserved and shared for future exposome research. D7.1 Medical University of Graz Report May 2020
Data availability confirmation An explicit confirmation that the data used in the project is publicly available and can be freely used for the purposes of the project. D1.3 Karolinska Institutet Report June 2020
Reference architecture Document describing the reference architecture for Information Commons and technical requirements. D10.1 CSC Report Jun 2020
EHEN Network website Website with network activities and links to all individual network websites D12.2 Karolinska Institutet Website Jun 2020
Improved wearable PEMs (Personal Exposome Monitors) A wearable and durable PEM that enables everyday monitoring of environmental exposure at the personal level and provides data for streaming and real-time monitoring D5.1 Karolinska Institutet Demonstrator Dec 2020
Bacterial and viral metagenomics High performance bioinformatics workflow for mining bacterial de novo analysis of viral genomes in metagenomic sequencing datasets genomes in NGS metagenomic sequencing datasets D9.1 ICM Demonstrator Dec 2020

March 12, 2015